Medical intelligence

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Adopted orphans as regulators of inflammation, immunity and skeletal homeostasis

By Natacha Ipseiz, Carina Scholtysek, Stephan Culemann, Gerhard Krönke − Adopted orphan nuclear receptors, such as peroxisome proliferator-activated receptors (PPARs) and liver X receptors (LXRs), have emerged as key regulators of inflammation and … [read more ...]

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Eroding students’ rural motivation: first do no harm?

By Samia A. Hurst − In the global scarcity of medical professionals, the clearest deficits of physicians exist precisely in the areas of the world where the need for them is greatest. Rather than only representing a missed opportunity for improving … [read more ...]

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Review articles

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Nanotechnology in medicine: European research and its implications

By Margarethe Hofmann-Amtenbrink et al. − In this study, we explore and discuss nanoparticles and nanoscale materials and their use in medicine (nanomedicine) and pharmaceutics (nanopharmaceutics). The study is aimed at shedding light on this … [read more ...]

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The painful primary hip replacement

By Csaba Forster-Horvath, Christian Egloff, Victor Valderrabano, Andrej M. Nowakowski − Patient satisfaction after total hip replacement is ­reported to be high, but subsequent chronic pain may be problematic. The rate of revision procedures due … [read more ...]

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Editorial

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Is Internet use unhealthy?

By Helena Fonseca − For clinicians who take care of adolescents this is a recurrent question in the course of a consultation, usually raised by parents. Who has never come across parents’ feelings of powerlessness regarding this issue?

Current opinion

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The Lausanne Institutional Biobank

By Vincent Mooser and Christine Currat − Breakthrough technologies which now enable the sequencing of individual genomes will irreversibly modify the way diseases are diagnosed, predicted, prevented and treated. … [read more...]

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Can geriatric approaches support the care of old patients in emergency departments?

By Andreas W. Schoenenberger, Aristomenis K. Exadaktylos − In the coming decades, the proportion of older emergency department patients is expected to increase continuously. These patients are at greater risk of adverse outcomes than younger … [read more...]

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The cardiorenal problem

By Emiliy Pollock and Albina Nowak − Cardiorenal syndrome refers to the increasingly recognised reciprocal association between cardiac and renal dysfunction, whereby injury to one organ ­directly promotes deterioration of the other. … [read more...]

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Original articles

CDC/ Dr. Ray Butler

Treatment outcomes of multidrug-resistant tuberculosis in Switzerland

By Peter Helbling et al. − Treatment outcomes for tuberculosis, resistant or not, were known to be satisfactory. The present study assessed, for the first time nationwide and using international standards, the outcomes of the more difficult to … [read more ...]

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White coat in primary care: what do patients think today?

By Paul Sebo, François R. Herrmann, Dagmar M. Haller − Patient preference for their doctor’s attire can influence their assessment of the quality of care. Our findings suggest that in Switzerland white coats are no longer considered a powerful … [read more ...]

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Is problematic internet use associated with somatic complaints?

By Joan-Carles Surís et al. − Excessive internet use has been associated with mental health problems, unhealthy behaviours, overweight and lack of sleep, but little is known about its association with other physical complaints. Excessive internet … [read more ...]

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Evaluation of prenatal diagnosis of congenital heart disease in a regional controlled case study

By Marie-Claude Rossier, Yvan Mivelaz, Marie-Claude Addor et al. − With the introduction of foetal ultrasonography in the early 1980s and the routine incorporation of cardiac scanning, it is now possible to diagnose a wide range of CHDs during … [read more ...]

Heart allocation and transplantation in Switzerland since the introduction of the Swiss Organ Allocation System

By Julius Weiss, Franziska Beyeler, Franz F. Immer, Swisstransplant Heart Working Group (STAH) − Switzerland is faced with an increasing number of patients waitlisted for a heart transplant. Compared with international data, the acceptance rate of … [read more ...]

street

Swiss monitoring of potential organ donors

By Julius H. Weiss, Isabelle Keel, Franz F. Immer, Jan Wiegand, Christoph Haberthür and the Comité National du Don d’Organes − Switzerland has one of the lowest post mortem organ donation rates in Europe. The main reason is the high number of … [read more ...]

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Early detection of subjects at risk for vascular remodelling

By Julia Dratva, Seraina Caviezel, Emmanuel Schaffner et al. − We present first Swiss data on CIMT from a population-based study. Analyses confirm the longitudinal impact of CVD risk factors on vessel health, and the predictive power of the risk … [read more ...]

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