Current opinion

Photo: CDC/ Melissa Dankel

Development of new antibiotics: taking off finally?

By Esther Bettiol and Stephan Harbarth – Antimicrobial resistance threatens modern day medicine. Research and development (R&D) of much-needed new antibiotics active against multiresistant pathogens is a key component of all programmes aiming … [read more...]

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Cardiovascular implantable electronic device infections

Because cardiac implantable electronic devices (CIEDs) improve symptoms and survival of patients with heart diseases their use has increased; simultaneously, the rate of CIED-associated infections has risen, from 1.53% in 2004 to 2.41% in 2008, … [read more...]

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Medical intelligence

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Salient features of the coronary collateral circulation

By Michael Stoller and Christian Seiler – The coronary collateral circulation provides an alternative source of blood supply to myocardium jeopardised by ischaemia. The protective effect of a well-developed coronary collateral circulation … [read more ...]

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Editorial

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Left ventricular thrombus ­formation after AMI

Left ventricular thrombus formation is a feared complication following acute myocardial infarction, predominantly owing to the risk of thromboembolism, in particular, stroke.

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Review articles

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Vaccination recommendations for adult patients with autoimmune inflammatory rheumatic diseases

By Silja Bühler, et al. – The number of individuals with autoimmune inflammatory rheumatic diseases (AIIRDs) treated with immunosuppressive drugs is increasing steadily. The immunosuppressants, as well as the AIIRD itself, increase the risk of … [read more ...]

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Biomedical informatics in Switzerland: need for action

By Christian Lovis and Jürg Blaser – Biomedical informatics is an umbrella scientific field that covers a broad spectrum of disciplines, from bioinformatics to clinical and public health informatics. It is becoming ever more important as eHealth … [read more ...]

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Original articles

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Adenocarcinoma of the gastrointestinal tract in lung transplanted patients with cystic fibrosis

Patients with cystic fibrosis are at risk of developing solid cancer following lung transplantation. This paper confirms this observation, describes gastric adenocarcinoma as a novel manifestation, and discusses potential mechanisms and implications. … [read more ...]

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Children hospitalised with ­pandemic influenza A/H1N1/09

By Andres Hagerman, et al. – This study reported the burden and outcome of a new ­pandemic influenza strain on a particularly vulnerable population: children. The strength of the study came from its nationwide aspect, revealing the true picture of … [read more ...]

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In-vitro induction of human ­regulatory T cells in pregnancy

By Natalie Marcoli, et al. – Treg expansion during normal pregnancy in order to suppress maternal alloresponses has mainly been shown in muri­ne models. This paper shows that the increased frequency of human CD4+CD25+FOXP3+ Tregs is mainly … [read more ...]

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