Editorial

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HIV is not transmitted under fully suppressive therapy: The Swiss Statement – eight years later

By Pietro L. Vernazza  and Edwin J. Bernard: Eight years ago, on January 30th 2008, the Swiss Federal Commission for AIDS-related Issues (“the Commission”, now the Swiss Federal Commission for Sexual Health) published a statement which – in the field of human immunodeficiency virus (HIV) – rapidly received the name “The Swiss statement”.

Current opinion

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“The obesity paradox” in disease

By Nina Braun, et al.:  Obesity may, counterintuitively, be protective and associated with greater survival in certain groups of people, such as the very elderly or those with certain chronic diseases – the “obesity paradox”. This article … [read more...]

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Medical intelligence

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How induced pluripotent stem cells are informing drug discovery in psychiatry

By Yishan Sun and Ricardo E. Dolmetsch: New laboratory techniques and collaborative efforts in psychiatric genetics are catalysing a rapid growth in knowledge around the neurobiological basis of mental and behavioral disorders. Among these new … [read more ...]

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Mesenchymal stem cells: myths and reality

By Adelaida Sarukhan, et al.: The number of studies addressing mesenchymal stem cell (MSC) biology and their capacity to treat a broad range of human diseases at the preclinical and clinical level has grown exponentially in the last two decades, with … [read more ...]

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Review articles

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The “Profiles” document

By Pierre-André Michaud, et al.: This article presents the proposed structure and content of Profiles, a new document which, in the future, will direct the format of undergraduate studies and of the Federal Licensing Examination. As Profiles is … [read more ...]

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In vivo imaging of cardiac development and function in zebrafish

By Michael Weber and Jan Huisken: Detailed studies of heart development and function are crucial for our understanding of cardiac failures and pave the way for better diagnostics and treatment. Recently, the powerful combination of the model system … [read more ...]

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Original articles

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Tuberculosis in early medieval Switzerland – osteological and molecular evidence

By Christine Cooper, et al.: The aim of this study was to assess the presence of tuberculosis in a rural early medieval population by means of a systematic investigation of bone lesions and molecular analyses of Myobacterium tuberculosis complex … [read more ...]

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Types of abuse and risk factors ­associated with elder abuse

By Simone Lacher, et al.: Only scarce data are available in Switzerland regarding ­elder abuse and neglect. This study described the frequency of the various types of abuse in victims suffering from elder abuse and the associated risk factors for … [read more ...]

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Alzheimer-type brain pathology may be transmitted by grafts of dura mater

By Karl Frontzek, et al.: Alzheimer’s disease  is characterized by progressive dementia and brain plaques consisting of the Aβ protein. Conventional wisdom has it that Alzheimer’s disease is not a transmissible disease. However, plaques … [read more ...]

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