Current opinion

Perioperative myocardial infarction/injury after noncardiac surgery

By Christian Puelacher, et al.: Perioperative myocardial infarction and injury (PMI) poses a problem more frequently than previously expected and is associated with a high mortality, thereby greatly contributing to postoperative mortality. Therefore, … [read more...]


Hypotestosteronaemia in the aging male: should we treat it?

By Nora Christe and Christoph A. Meier: Classical hypogonadism linked to an underlying disease, such as a pituitary tumour, is a distinct indication for androgen substitution. But how about the aging male? Testosterone declines in the aging male and … [read more...]

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Medical intelligence


Do we still need surveillance for human prion diseases?

By Herbert Budka and Robert G. Will: The epidemics of classical bovine spongiform encephalopathy (BSE) and variant Creutzfeldt-Jakob disease related to BSE-infected food are coming to an end. The decline in concern about these diseases may invite … [read more ...]


The regulation of exosome ­function in the CNS: implications for neurodegeneration

By Francesca Properzi, et al.: Exosomes are nanovesicles that have been shown to regulate neuronal development and regeneration, and modulate synaptic function. In the central nervous system, exosomal function is highly regulated and might have a … [read more ...]

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Review articles

© Qwasyx |

How the Mediterranean diet and some of its components modulate inflammatory pathways in arthritis

By Francesca Oliviero, et al.: The Mediterranean diet model has already been linked to a number of beneficial health effects: important anti-inflammatory activities by affecting the arachidonic acid cascade, the expression of some proinflammatory … [read more ...]

© Michal Bednarek |

Iron deficiency in sports

By German E. Clénin, et al.: Iron deficiency in sports is frequent and relevant, as all stages of iron deficiency – iron deficiency anaemia, iron deficiency and/or microcytosis and hypochromia – affect physical performance. It is thus important … [read more ...]

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Original articles


Too frequent low-dose methotrexate prescriptions

By Sascha Karlen, et al.: Erroneous too frequent low-dose methotrexate prescriptions have a high potential for harmful overdosing. This study provides a comprehensive analysis of the incidence of errors, suggesting the need for quality assurance … [read more ...]


Total inpatient treatment costs in patients with severe burns

By Tarun Mehra, et al.: Reimbursement systems, especially those which are based on DRGs, have difficulties depicting the actual cost of burn treatment, leaving care providers with a significant financial burden. … [read more ...]


Outcome after airway intervention in laryngeal carcinoma

Airway intervention in the form of tracheostomy or ­trans-oral laser debulking is performed as an emergency life-saving procedure. Controversy exists as to the risk ­associated with antecedent airway intervention before ­definitive treatment of … [read more ...]

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